Why the study?
Does growth hormone replacement therapy improve clinical outcomes and cardiovascular risk factors in adults with growth hormone deficiency?
Does growth hormone replacement therapy improve clinical outcomes and cardiovascular risk factors in adults with growth hormone deficiency?
Growth hormone replacement therapy in adults with severe deficiency offers multiple benefits including improved body composition and cardiovascular risk factors, provided it is carefully titrated to avoid fluid retention.
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May support titrated GHRT in severe adult GHD; leaves open RCTs on hard cardiovascular outcomes.
Alexopoulou et al. (2010) studied this question.
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