Adrenal Necrosis in the Acquired Immunodeficiency Syndrome

Brief Reports1 February 1984Adrenal Necrosis in the Acquired Immunodeficiency SyndromeMICHAEL L. TAPPER, M.D., HEIDRUN Z. ROTTERDAM, M.D., CHESTER W. LERNER, M.D., KATHLEEN AL'KHAFAJI, M.D., PETER A. SEITZMAN, M.D.MICHAEL L. TAPPER, M.D., HEIDRUN Z. ROTTERDAM, M.D., CHESTER W. LERNER, M.D., KATHLEEN AL'KHAFAJI, M.D., PETER A. SEITZMAN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-100-2-239 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince 1980, the medical community has seen an epidemic of opportunistic infections and unusual malignancies now known as the acquired immunodeficiency syndrome. In autopsies done on ten patients who died of this syndrome at the Lenox Hill Hospital, we have noted adrenal necrosis to be a strikingly common finding in male homosexual patients with evidence of localized or disseminated cytomegalovirus infection at the time of death. We report our findings to alert clinicians to the frequency of "adrenalitis" and the potential for adrenal insufficiency in patients with the acquired immunodeficiency syndrome.Between March 1981 and March 1983, complete autopsies were...References1. Update on acquired immune deficiency syndrome (AIDS)—United States. MMWR. 1982;31:507-8, 513-4. MedlineGoogle Scholar2. NELSON J and WYATT J. Salivary gland virus disease. Medicine (Baltimore). 1959;38:223-41. CrossrefMedlineGoogle Scholar3. WONG J and WARNER N. Cytomegalic inclusion disease in adults. Arch Pathol. 1962;74:403-22. MedlineGoogle Scholar4. DUVALL C, CASAZZA A, GRIMLEY P, CARBONE P, and ROWE W. Recovery of cytomegalovirus from adults with neoplastic disease. Ann Intern Med. 1966;64:531-41. LinkGoogle Scholar5. EVANS D and WILLIAMS E. Cytomegalic inclusion disease in the adult. J Clin Pathol. 1968;21:311-6. CrossrefMedlineGoogle Scholar6. ROSEN P and HAJDU S. 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TAPPER, M.D.; HEIDRUN Z. ROTTERDAM, M.D.; CHESTER W. LERNER, M.D.; KATHLEEN AL'KHAFAJI, M.D.; PETER A. 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PESANTI, M.D. 1 February 1984Volume 100, Issue 2Page: 239-241KeywordsAIDSAntimicrobialsAutopsyChemotherapyCytomegalovirus infectionHomosexualsMicrobiologyNecrosisOpportunistic infectionsResearch laboratories ePublished: 1 December 2008 Issue Published: 1 February 1984 PDF downloadLoading ...