Why the study?
Does discontinuing enoxaparin 12-24 hours before delivery increase the risk of hemorrhagic complications in pregnant women compared to untreated women?
Population
16,416 pregnant women (n=284 treated with enoxaparin during pregnancy, n=16,132 untreated)
Comparison
Enoxaparin therapy during pregnancy… vs No enoxaparin treatment during pregnancy
Design
Cohort
Follow-up
Postpartum
Authors
Loading...
Supports 12-24 hour enoxaparin discontinuation pre-delivery without excess hemorrhage; leaves open confirmation in randomized trials.
Does discontinuing enoxaparin 12-24 hours before delivery increase the risk of hemorrhagic complications in pregnant women compared to untreated women?
Discontinuing enoxaparin 12-24 hours before delivery does not increase the risk of maternal hemorrhagic complications compared to untreated women, suggesting a shorter discontinuation window than the currently recommended 24 hours may be safe.
Maslovitz et al. (2005) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: