Why the study?
The study was conducted to assess and synthesize published prospective cohort studies on the association between atrial fibrillation and dementia incidence.
Does atrial fibrillation increase the incidence of dementia in patients with normal baseline cognitive function?
Does atrial fibrillation increase the incidence of dementia in patients with normal baseline cognitive function?
This meta-analysis confirms that atrial fibrillation is an independent risk factor for incident dementia, highlighting the need for cognitive screening in this population.
Answers are grounded in this paper and cite their sources.
Supports cognitive screening in AF patients; confirms independent dementia risk beyond stroke in preserved cognition.
OBJECTIVES: To assess and synthesize the prospective cohort studies published so far on the association between atrial fibrillation (AF) and dementia incidence. METHODS: test and funnel plot, respectively. RESULTS: test and funnel plot, we did not detect obvious heterogeneity and publication bias in our study. Meta-regression on age did not find significant results. CONCLUSIONS: The results of our meta-analysis further confirmed that AF was an independent risk factor for dementia in patients with normal baseline cognitive function not suffering from acute stroke. Screening for dementia in AF patients and including dementia as an independent outcome in large AF treatment trials is warranted.
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Liu et al. (2019) studied this question.
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