August 8, 2013Journal of Endourology

Fluorodeoxyglucose-Positron-Emission Tomography/Computed Tomography Imaging for Adrenal Masses in Patients with Lung Cancer: Review and Diagnostic Algorithm

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Why the study?

Does FDG-PET/CT accurately predict adrenal gland metastasis in patients with NSCLC?

Population

345 patients with non-small cell lung cancer and adrenal lesions

Comparison

Fluorodeoxyglucose-Positron-Emission… vs Histological confirmation or alternative imaging

Design

Review

Authors

WSWilliam Z. StoneUniversity of Florida DWDavid C. WymerUniversity of Florida BCBenjamin K. CanalesUniversity of Florida

Discussion

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Implication

Caution against relying on FDG-PET/CT alone for adrenal metastasis in NSCLC; leaves open the need for prospective histological validation.

Structured PICO

Does FDG-PET/CT accurately predict adrenal gland metastasis in patients with NSCLC?

Population

345 patients (343 from 7 reviewed articles + 2 case reports) with non-small cell lung cancer (NSCLC) and adrenal lesions

Intervention

Fluorodeoxyglucose-Positron-Emission Tomography/Computed Tomography (FDG-PET/CT) imaging

Comparator

Histological confirmation (adrenal biopsy or adrenalectomy) or alternative imaging

Outcome

Accuracy (sensitivity and specificity) of FDG-PET/CT to predict adrenal gland metastasissurrogate

While FDG-PET/CT has high sensitivity and specificity for adrenal metastasis in NSCLC, histological confirmation or secondary imaging is recommended due to false positives.

Cite This Study

Stone et al. (2013) studied this question.

synapsesocial.com/papers/6a83cc33048eca62454d8a7a https://doi.org/10.1089/end.2013.0380

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Implication

Caution against relying on FDG-PET/CT alone for adrenal metastasis in NSCLC; leaves open the need for prospective histological validation.

Fluorodeoxyglucose-Positron-Emission Tomography/Computed Tomography Imaging for Adrenal Masses in Patients with Lung Cancer: Review and Diagnostic Algorithm

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Fluorodeoxyglucose-Positron-Emission Tomography/Computed Tomography Imaging for Adrenal Masses in Patients with Lung Cancer: Review and Diagnostic Algorithm

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

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