Why the study?
In patients with HFpEF or HFmrEF, treatments reduce heart failure hospitalizations rather than improve survival, but recurrent admissions may impair activities of daily living and increase societal burden.
Does the frequency of recurrent heart failure hospitalizations predict a decline in activities of daily living in patients with HFpEF or HFmrEF?
Does the frequency of recurrent heart failure hospitalizations predict a decline in activities of daily living in patients with HFpEF or HFmrEF?
Recurrent heart failure hospitalizations independently predict a decline in activities of daily living among patients with HFpEF or HFmrEF, highlighting the functional importance of preventing readmissions.
Recurrent HF hospitalizations may impair ADL in HFpEF/HFmrEF; hypothesis-generating and requires prospective confirmation before guiding care.
Background: For patients with heart failure (HF) and preserved ejection fraction (HFpEF) or mildly reduced ejection fraction (HFmrEF), there is no treatment that improves survival, but some will reduce HF hospitalizations. Recurrent HF admissions may impair activities of daily living (ADL) and increase the societal burden. Methods and Results: We analyzed 130 patients with HFpEF or HFmrEF who had recurrent HF hospitalizations. The multivariate linear mixed-effects model revealed that HF hospitalization frequency remained an independent predictor of ADL decline, as evaluated by the Barthel index. Conclusions: Recurrent hospitalization for HF contributes to ADL decline. Preventing rehospitalization due to HF is crucial.
No takes yet. Share an insight, caveat, or question.
Ozaki et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: