Why the study?
Does combination therapy with an ACE inhibitor and a calcium channel blocker reduce cardiovascular events in patients with systolic hypertension?
Does combination therapy with an ACE inhibitor and a calcium channel blocker reduce cardiovascular events in patients with systolic hypertension?
This paper discusses the context and implications of the ACCOMPLISH trial for the management of hypertension.
Contextualizes ACCOMPLISH for hypertension care; leaves optimal combinations open for further study.
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McAlister et al. (2010) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: