Clinical Evaluation of High-Resolution MRI Combined With DWI In Identifying Vulnerable Carotid Plaque

Objective: High-resolution magnetic resonance imaging (HR-MRI) combined with diffusion weighted imaging (DWI) is used to identify Vulnerable plaques (VP) and their characteristic components, and apparent diffusion coefficient (ADC) correlation analysis with serum inflammatory markers to assess plaque vulnerability. Methods: Into eligible 60 patients, including vulnerable plaques group (VP group) of 29 cases and the non-vulnerable plaques group (N group) of 31 cases, measure the two groups of the average ADC, serum levels of inflammatory markers [high-sensitivity C-reactive protein (hs-CRP), myeloperoxidase (MPO) and erythrocyte sedimentation rate (ESR) ], compared the VP plaque characteristics of different components and the level of blood vessel walls of ADC, assessment of patients with serum levels of inflammatory markers plaques ADC average correlation. Results: The results showed that the ADC mean value of the plaques in the VP group was significantly lower than that in the N group, and the levels of hs-CRP and MPO were correlated with the ADC mean value of the plaques. Conclusion: The ADC value of plaque measured by HR-MRI combined with DWI sequence can quantify the identification of vulnerable plaque and its characteristic components, reflect the inflammation of plaque to a certain extent, and thus prevent and treat stroke and other adverse outcomes more effectively.