Why the study?
Does myocardial infarction-induced congestive heart failure cause differential changes in adenylyl cyclase activities in the left and right ventricles of rats?
Does myocardial infarction-induced congestive heart failure cause differential changes in adenylyl cyclase activities in the left and right ventricles of rats?
Congestive heart failure following myocardial infarction in rats leads to differential, severity-dependent alterations in adenylyl cyclase activity and beta-receptor density between the left and right ventricles.
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Suggests asymmetric post-MI beta-adrenergic remodeling; hypothesis-generating in animal models, with no immediate clinical implications.
Sethi et al. (1997) studied this question.
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