Why the study?
Does exogenous norepinephrine elicit attenuated cutaneous vasoconstriction in older compared to young humans?
Population
22 men and women, comprising 11 young (18-30 years) and 11 older (62-76 years) subjects.
Comparison
Exogenous norepinephrine infused via intradermal… vs Control site infused with Ringer solution, and…
Design
Cross-sectional
Authors
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Blunted cutaneous vasoconstriction to norepinephrine may heighten cold-induced heat loss risk in older adults; leaves open its contribution to age-related thermoregulatory impairment.
Does exogenous norepinephrine elicit attenuated cutaneous vasoconstriction in older compared to young humans?
Norepinephrine-mediated cutaneous vasoconstriction is blunted in older humans, which may predispose them to excess heat loss in cold environments.
Thompson et al. (2005) studied this question.
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