Why the study?
Does Prostaglandin E2 infusion induce therapeutic abortion in pregnant women?
Does Prostaglandin E2 infusion induce therapeutic abortion in pregnant women?
Prostaglandin E2 infusion is effective for inducing therapeutic abortion with no serious adverse effects noted.
This is the authors' abstract. We don't add key points for this paper.
Summary Prostaglandin E 2 was infused in 139 women recommended for therapeutic trmination of pregnancy. Abortion occurred in 130 women and was complete in 105. Uterine activity was measured in 67 patients before, during and after prostagiandin infusion. In selected cases haematological, biochemical, hormonal and renal function studies were performed. No serious adverse effects were noted.
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May support prostaglandin E2 for therapeutic abortion; hypothesis-generating and should not change practice without controlled trials.
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Karim et al. (1972) studied this question.
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