Why the study?
Do local blood flow regulation mechanisms (veno-arteriolar axon reflex and myogenic mechanisms) contribute to the maintenance of arterial pressure in the upright position during central sympathetic blockade?
Population
5 normal subjects
Comparison
Epidural anesthesia to induce central… vs Injection of phentolamine into the femoral vein…
Design
Other
Authors
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Local reflexes sustain pressure during sympathetic blockade; hypothesis-generating for orthostatic control, needs confirmation before clinical consideration.
Do local blood flow regulation mechanisms (veno-arteriolar axon reflex and myogenic mechanisms) contribute to the maintenance of arterial pressure in the upright position during central sympathetic blockade?
The local veno-arteriolar axon reflex and myogenic mechanisms actively contribute to maintaining arterial blood pressure in the upright position when central sympathetic control is blocked.
Henriksen et al. (1983) studied this question.
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