What question did this study set out to answer?

To report a case of ventricular tachycardia provoked by moderate doses of thioridazine and evaluate the efficacy of artificial internal pacing after standard medical interventions failed.

November 1, 1966Annals of Internal Medicine

Thioridazine (Mellaril®)-induced Ventricular Tachycardia Controlled with an Artificial Pacemaker

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Why the study?

Does an internal pacemaker control thioridazine-induced ventricular tachycardia in a patient failing usual therapeutic measures?

Population

1 patient admitted for evaluation of schizophrenia who developed ventricular tachycardia secondary to…

Design

Case_report

Authors

FSFred W. SchoonmakerSt. Luke's-Roosevelt Hospital Center

Discussion

Member takes

Implication

May support pacing in refractory thioridazine-induced VT; leaves open generalizability and need for prospective data.

Key Points

To report a case of ventricular tachycardia provoked by moderate doses of thioridazine and evaluate the efficacy of artificial internal pacing after standard medical interventions failed.
Assessed a 50-year-old male undergoing evaluation for schizophrenia who developed ventricular tachycardia secondary to moderate thioridazine therapy (N=1).
Instituted artificial internal cardiac pacing following the failure of standard antiarrhythmic pharmacotherapies to suppress the ventricular rhythm.
Moderate therapeutic doses of thioridazine provoked sustained ventricular tachycardia.
Internal artificial cardiac pacing successfully suppressed the refractory arrhythmia and restored ventricular rate control.

Structured PICO

Does an internal pacemaker control thioridazine-induced ventricular tachycardia in a patient failing usual therapeutic measures?

Population

1 patient (50-year-old Negro man) admitted for evaluation of schizophrenia who developed ventricular tachycardia secondary to moderate amounts of thioridazine.

Intervention

Internal artificial pacemaker

Outcome

Control of ventricular tachycardiahard clinical

This early case report demonstrates the successful use of an artificial pacemaker to control drug-induced (thioridazine) ventricular tachycardia refractory to standard therapies.

Cite This Study

Fred W. Schoonmaker (1966) studied this question.

synapsesocial.com/papers/6a83fa7a53408ed95e4d92cc https://doi.org/10.7326/0003-4819-65-5-1076

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Thioridazine (Mellaril®)-induced Ventricular Tachycardia Controlled with an Artificial Pacemaker

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Thioridazine (Mellaril®)-induced Ventricular Tachycardia Controlled with an Artificial Pacemaker

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

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