April 1, 1978Pacing and Clinical Electrophysiology

Effect of Electroconvulsive Therapy on Cardiac Rhythm, Conduction and Repolarization*

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Why the study?

Does electroconvulsive therapy alter cardiac rhythm, conduction, and repolarization in psychiatric patients without known heart disease?

Population

15 psychiatric patients without known heart disease, all taking psychotropic drugs.

Comparison

Electroconvulsive therapy following… vs Baseline values obtained after atropine…

Design

Cohort

Follow-up

24 hours

Authors

PTPaul J. TroupMemorial Hermann JSJoyce G. SmallIndiana University – Purdue University Indianapolis VMVictor MilsteinLarue Carter Hospital

Discussion

Member takes

Implication

QTc prolongation after ECT warrants monitoring; leaves arrhythmic risk open in broader psychiatric cohorts.

Structured PICO

Does electroconvulsive therapy alter cardiac rhythm, conduction, and repolarization in psychiatric patients without known heart disease?

Population

15 psychiatric patients (male: 8, female: 7, age: 19-51, mean: 29.8) without known heart disease, all taking psychotropic drugs.

Intervention

Electroconvulsive therapy (ECT) (25 episodes) following premedication with atropine (0.4-1.2 mg, mean: 1.1 mg IV), methohexital, and succinylcholine.

Comparator

Baseline values obtained after atropine administration but prior to ECT.

Outcome

Changes in cardiac rhythm, conduction, and repolarization (heart rate, PR interval, QTc interval, PVC, PAC) measured by 24-hour Holter recordings.surrogate

Electroconvulsive therapy induces significant changes in heart rate, PR, and QTc intervals due to autonomic stimulation, but does not provoke arrhythmias in psychiatric patients without underlying heart disease.

Limitations

Possible antiarrhythmic role of psychotropic agents or premedication is unknown

Cite This Study

Troup et al. (1978) studied this question.

synapsesocial.com/papers/6a83faa32b578ef1603e9a4c https://doi.org/10.1111/j.1540-8159.1978.tb03461.x

View Full Paper

Ask AI

Bookmark

Effect of Electroconvulsive Therapy on Cardiac Rhythm, Conduction and Repolarization*

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Effect of Electroconvulsive Therapy on Cardiac Rhythm, Conduction and Repolarization*

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider