Key result
Submucosal epinephrine during septoplasty triggers ventricular tachycardia and arrest in undiagnosed variant angina.
Why the study?
Local infiltration of epinephrine during septal surgery can cause side effects including arrhythmia, but reports of ventricular tachycardia after appropriate dosing are rare.
Case Report (n=1)
Submucosal epinephrine injection during septoplasty can trigger life-threatening ventricular tachycardia, which may unmask underlying variant angina pectoris.
Answers are grounded in this paper and cite their sources.
Epinephrine infiltration warrants caution during septoplasty; leaves open whether variant angina screening could identify at-risk patients.
Local infiltration of dilute solutions of epinephrine is widely used for the purpose of hemostasis during septal surgery.However, infiltrated epinephrine often make several side effects such as palpitation, hypertension, or arrhythmia.Also, it may be possible to experience the catastrophic events such as intracranial hemorrhage, pulmonary edema, and cardiac arrest when we use overdose of epinephrine.We experienced ventricular tachycardia in a 36-year-old male with no significant medical history, after submucosal infiltration of epinephrine with appropriate dose during septoplasty.Intraoperative cardiopulmonary resuscitation by external chest compression and direct current cardioversion was successful.We thoroughly evaluated the patient and proved the diagnosis of variant angina pectoris using coronary angiography.(Korean J Otorhinolaryngol-Head Neck Surg 2009;52:98-101) KEY WORDS：Epinephrine•Variant angina pectoris•Ventricular tachycardia. 서 론Epinephrine은 lidocaine과 혼합하여 이비인후과 영역을 비롯하여 많은 수술의 국소주사제로 흔히 사용되고 있다.특 히 비중격성형술 과정에서 출혈과 점막의 울혈 감소, 수술 시야 개선,
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Lee et al. (2009) conducted a case report in Ventricular tachycardia and variant angina pectoris (n=1). Epinephrine was evaluated on Development of ventricular tachycardia. Submucosal infiltration of epinephrine during septoplasty provoked severe ventricular tachycardia and cardiac arrest in a 36-year-old male who was subsequently diagnosed with variant angina pectoris.
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