Population
38 pentobarbital anesthetized dogs
Comparison
Methylene blue and ETYA vs Control conditions
Design
Preclinical
Authors
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Supports cGMP and arachidonic acid pathways in flow dilation; leaves open human relevance.
Flow-dependent dilation in the canine femoral artery involves both cyclic GMP and a non-prostaglandin metabolite of arachidonic acid.
Kaiser et al. (1986) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: