Population
Six Kaposi's sarcoma cell cultures derived from four subjects with iatrogenic, sporadic and acquired immune…
Design
Preclinical
Authors
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Challenges endothelial origin of KS spindle cells in models; leaves open myofibroblast role in human pathogenesis.
In vitro analysis suggests that Kaposi's sarcoma-derived spindle cells exhibit a myofibroblast phenotype rather than an endothelial one, indicating the in vivo endothelial population may represent reactive hyperplasia.
Simonart et al. (2000) studied this question.
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