The Use of Tetraethylammonium Bromide as a Diagnostic Test for Pheochromocytoma

Case Reports1 November 1948THE USE OF TETRAETHYLAMMONIUM BROMIDE AS A DIAGNOSTIC TEST FOR PHEOCHROMOCYTOMAJOHN S. LADUE, M.D., Ph.D., F.A.C.P., PAUL J. MURISON, M.D., GEORGE T. PACK, M.D.JOHN S. LADUE, M.D., Ph.D., F.A.C.P., PAUL J. MURISON, M.D., GEORGE T. PACK, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-29-5-914 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONThe purpose of this case report is to present and compare the reactions of a patient with a medullary tumor of the adrenal gland (pheochromocytoma) to the intravenous administration of histamine phosphate and of tetraethylammonium bromide.Roth and Kvale1found that three patients with pheochromocytoma who were given 1/40 to 1/20 of a milligram of histamine phosphate intravenously responded with a rise of 100 mm. of Hg or more in the blood pressure reading. Patients who had essential hypertension or hypertension secondary to renal disease and those who were controls or hyper-reactors to the cold pressor test evidenced a...Bibliography1. ROTHKVALE GMWF: Tentative test for pheochromocytoma, Am. Jr. Med. Sci., 1945, ccx, 653-660. CrossrefGoogle Scholar2. BELTPOWELL AETO: Clinical manifestations of chromaffin cell tumors arising from suprarenal medulla; suprarenal sympathetic syndrome, Surg., Gynec. and Obst., 1934, lix, 9-24. Google Scholar3. HYMANMENCHER AWH: Pheochromocytoma of adrenal gland, Jr. Urol., 1943, xlix, 755-776. CrossrefGoogle Scholar4. GREEN DM, Pheochromocytoma and chronic hypertension, Jr. Am. Med. Assoc., 1946, cxxxi, 1260-1265. CrossrefGoogle Scholar5. MACKENZIEMCEACHERN DWD: Tumor of medulla of adrenal (adrenal pheochromocytoma) with removal and relief of paroxysmal hypertension, Jr. Urol., 1938, xl, 467-476. CrossrefGoogle Scholar6. BEERKINGPRINZMETAL EFHM: Pheochromocytoma with demonstration of pressor (adrenalin) substance in blood preoperatively during hypertensive crises, Ann. Surg., 1937, cvi, 85-91. CrossrefGoogle Scholar7. ACHESONMOE GHGK: Some effects of tetraethylammonium on mammalian heart, Jr. Pharmacol. and Exper. Therap., 1945, lxxxiv, 189-195. Google Scholar8. LYONS R: Personal communication. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.Read before the American Federation for Clinical Research, Chicago, Illinois, April 27, 1947.*Received for publication April 30, 1947.From The Pack Medical Group, New York, N. Y. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPHEOCHROMOCYTOMAPhæOchromocytoma a report of two cases with a review of the diagnostic testsThe dynamics of quantifiable homeostasis I. The individualThe Incidence of Phaeochromocytoma in the NetherlandsEffect of infusion of saline on response of blood pressure to intravenous tetraethylammonium chlorideThe effect of sympathetic blockade or hyperventilation on epinephrine-induced cardiac arrhythmias during anaesthesia with halothane and methoxyfluraneGanglion-Blocking Agents in HypertensionPhaeochromocytomaHypertonieHypertoniePheochromocytoma: A review of the literatureEndokrinologische UntersuchungsmethodenThe adrenals and the anaesthetistHypertension during operation.PHEOCHROMOCYTOMA: THE VALUE OF CERTAIN TESTS USED ROUTINELY IN DIAGNOSIS*EDWARD S. ORGAIN, M.D., F.A.C.P.PHAEOCHROMOCYTOMA ASSOCIATED WITH NEUROFIBROMATOSISPHAOCHROMOCYTOMA OF THE ADRENAL WITH PAROXYSMAL HYPERTENSIONPHEOCHROMOCYTOMA: TWO CASE REPORTS WITH UNUSUAL REACTIONS AND A GENERAL REVIEW*CHARLIE F. WINGO, M.D., JOHN P. WILLIAMS, M.D., F.A.C.P., FRANK A. 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SHOEMAKER, Ph.D., STEWART WOLF, M.D., F.A.C.P.Die NebenniereTHE TREATMENT OF HYPERTENSION WITH DRUGS*MILTON MENDLOWITZ, M.D., F.A.C.P.Essential Hypertension in a 12 Year Old Girl Treated with Hexamethonium CompoundsTHE LIND BICENTENARYPHÆOCHROMOCYTOMAZur Diagnostik und Therapie der Ph�ochromocytomeRenal Cyst Simulating PheochromocytomaThe use of pharmacological tests in the diagnosis of pheochromocytomaRe-evaluation of the reliability of pharmacologic and cold pressor studies in hypertension and pheochromocytomaPharmacologic basis of various tests used in the diagnosis of pheochromocytomaPheochromocytoma with false negative benzodioxane testsVASOPRESSOR COMPONENTS OF PHEOCHROMOCYTOMAS*KARL H. BEYER, Ph.D., M.D., F.A.C.P., CHARLES A. ROSS, M.S., VIRGIL D. WIEBELHAUS, Ph.D., WILLIAM S. WALLER, B.S., GRACE S. SCHUCHARDT, B.S.The Use of Dibenamine and Norepinephrine in the Operative Treatment of PheochromocytomaAdrenal medullary functionUntoward Reactions to Tests for Epinephrine-Secreting Tumors (Pheochromocytoma)Newer concepts of the role of sodium in diseasePheochromocytoma1Pharmacologic and physiologic studies of a case of pheochromocytomaPHÆOCHROMOCYTOMA OF THE ADRENALPheochromocytomaPheochromocytoma Complicating PregnancyThe Differential Diagnosis of PheochromocytomaAdrenal medullary tumor (pheochromocytoma)Some Kinds of Hypertension Which Demand SurgeryThe Cardiovascular Effects of Tetraethylammonium in Animals and Man, with Special Reference to Hypertension 1 November 1948Volume 29, Issue 5Page: 914-921KeywordsAdrenal glandsBlood pressureHistamineHypertensionPheochromocytomaPhosphatesRenal diseasesSecondary hypertension ePublished: 1 December 2008 Issue Published: 1 November 1948 PDF downloadLoading ...