Cancer poses a severe threat to human life and health. In recent years, immunotherapy has been widely used in cancer treatment. However, easy recurrence, drug resistance, and side effects have become urgent issues to be solved. Nano-drug delivery systems loaded with anti-tumor drugs have many advantages, including powerful targeting, high safety, and low side effects. Based on this, applying nano-drug delivery systems in immunotherapy is a research hotspot. This paper reviews the application status and research progress of nano-drug delivery systems in tumor immunotherapy. The history and types of nanocarriers and the current status of bispecific nanobodies and nucleic acid drugs are presented.
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