Why the study?
Does standard heart failure therapy improve left ventricular noncompaction in a patient presenting with heart failure?
Does standard heart failure therapy improve left ventricular noncompaction in a patient presenting with heart failure?
Standard heart failure therapy can lead to marked echocardiographic improvement in patients with left ventricular noncompaction cardiomyopathy.
Suggests standard medical therapy may reverse structural abnormalities in left ventricular noncompaction; leaves open whether these.
Isolated ventricular noncompaction, a rare genetic cardiomyopathy, is thought to be caused by the arrest of normal myocardial morphogenesis. It is characterized by prominent, excessive trabeculation in a ventricular wall segment and deep intertrabecular recesses perfused from the ventricular cavity. The condition can present with heart failure, systematic embolic events, and ventricular arrhythmias. Two-dimensional echocardiography is the typical diagnostic method. We report a case of heart failure in a 35-year-old man who presented with palpitations. Two-dimensional echocardiograms revealed left ventricular noncompaction, which markedly improved after standard heart failure therapy.
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Papadopoulos et al. (2017) studied this question.
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