Why the study?
Does injection of partially purified rat renin affect blood pressure and renin levels in bilaterally nephrectomized rats?
Does injection of partially purified rat renin affect blood pressure and renin levels in bilaterally nephrectomized rats?
The study demonstrates that circulating renin is taken up by vascular tissue and the pressor response to exogenous renin is related to aortic but not plasma renin.
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Supports experimental vascular renin uptake; leaves open relevance to human hypertension.
Loudon et al. (1982) studied this question.
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