March 1, 1978The Journal of Clinical Endocrinology & Metabolism
Plasma Angiotensin Converting Enzyme Activity in Mother and Fetus*
Why the study?
Does the mode of delivery (cesarean section vs. spontaneous vaginal delivery) affect plasma angiotensin converting enzyme activity in mothers and fetuses at term?
Population
Normal mothers and fetuses at term
Comparison
Elective cesarean section vs Spontaneous vaginal delivery
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Maternal ACE elevation at cesarean warrants no practice change; Level 4 data leave causal fetal-maternal renin-angiotensin effects open.
Structured PICO
Does the mode of delivery (cesarean section vs. spontaneous vaginal delivery) affect plasma angiotensin converting enzyme activity in mothers and fetuses at term?
P
Population
Normal mothers and fetuses at term
I
Intervention
Elective cesarean section
C
Comparator
Spontaneous vaginal delivery
O
Outcome
Plasma converting enzyme activitysurrogate
Maternal plasma ACE activity is elevated during cesarean section compared to vaginal delivery, while fetal ACE activity remains unaffected by the delivery method.
Cite This Study
Oparil et al. (1978) studied this question.