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November 18, 2024Research Journal of Pharmacy and Technology

The Impact of Medication Compliance on mild Cognitive Impairment in Hypertensive Individuals: A Cohort Study

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Why the study?

The study was designed to evaluate whether antihypertensive drug compliance protects against mild cognitive impairment and to assess the prevalence and factors associated with MCI among older adults in an Indian population.

Does compliance to antihypertensive medication prevent mild cognitive impairment in older adults with hypertension?

Population

168 subjects aged ≥50 years with hypertension ≥5 years without dementia in India

Comparison

Antihypertensive drug compliance vs non-compliance

Design

Cohort study

Authors

SYShalini YadavMax-Planck-Institut für KohlenforschungSSSunil Dutt SharmaWest Virginia UniversityBYBir Singh YadavEmployees State Insurance Post Graduate Institute of Medical Sciences and Research

Discussion

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Member takes

Overview

Antihypertensive compliance was associated with lower cognitive impairment; leaves open whether it prevents MCI in older hypertensives.

Structured PICO

Does compliance to antihypertensive medication prevent mild cognitive impairment in older adults with hypertension?

P
Population
168 subjects aged ≥50 years with hypertension for ≥5 years, without dementia (ICD-10 criteria), in an Indian population. Mean age 59.92 years, female-dominated, 57.73% from a rural background.
I
Intervention
Compliance to antihypertensive medication
C
Comparator
Non-compliance to antihypertensive medication
O
Outcome
Mild cognitive impairment assessed by Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA)surrogate

Compliance to antihypertensive medication is associated with a significantly lower prevalence of mild cognitive impairment and better cognitive scores in older hypertensive patients.

Cite This Study

Yadav et al. (2024) studied this question.

synapsesocial.com/papers/6a841474309bd08d9172facehttps://doi.org/10.52711/0974-360x.2024.00796
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Also Consider

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