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August 1, 2018Clinical Interventions in AgingOpen Access

Cognitive impairment was significantly associated with poorer treatment adherence in elderly hypertensive patients, with each additional point on the MMSE lowering the HBCS nonadherence score by 0.19 points.

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Population

300 elderly patients aged 65–91 years (mean age 71.8) diagnosed with hypertension.

Design

Cross-sectional

Key result

Cognitive impairment was significantly associated with poorer treatment adherence in elderly hypertensive patients, with each additional point on the MMSE lowering the HBCS nonadherence score by 0.19 points.

Authors

ACAnna ChudiakIUIzabella UchmanowiczGMGrzegorz Mazur

Discussion

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Overview

Supports cognitive screening to flag adherence risks in elderly hypertensives; leaves open causal effects and intervention benefits.

Key Points

  • To determine the prevalence of cognitive impairment and evaluate its effect on treatment adherence and compliance among elderly individuals with hypertension.
  • Conducted an analytical cross-sectional study in 300 patients aged 65–91 years (mean age = 71.8 ± 7.8 years) diagnosed with hypertension.
  • Evaluated cognitive function and adherence using the Mini–Mental State Examination (MMSE), the Hill-Bone High Blood Pressure Compliance Scale (HBCS), and clinical records.
  • Cognitive impairment occurred in 60% of patients, and 63% demonstrated compliance with antihypertensive therapy (mean HBCS score: 20.8 points).
  • Cognitive impairment correlated strongly with total HBCS adherence scores (p < 0.001) as well as the appointment keeping (p < 0.001) and medication taking (p < 0.001) subscales.
  • Higher educational attainment was associated with superior compliance, whereas male sex negatively influenced treatment adherence.

Study Design

Type

Cross-Sectional (n=300)

Multicenter

No

Structured PICO

P
Population
300 elderly patients (mean age 71.8 years, 55.7% female) with aggravated hypertension treated at a single center in Poland.
O
Outcome
Treatment compliance and adherence measured by the Hill-Bone High Blood Pressure Compliance Scale (HBCS) and its correlation with cognitive impairment measured by the Mini-Mental State Examination (MMSE).patient reported

Main Result

Effect estimate: β -0.19 (95% CI -0.29 to -0.09)

p-value: p=<0.001

Cognitive impairment is highly prevalent in elderly hypertensive patients and is strongly associated with poorer adherence to antihypertensive therapy.

Limitations

  • Study sample was recruited from a single center

Cite This Study

Chudiak et al. (2018) conducted a cross-sectional in Hypertension (n=300). Cognitive impairment vs. Normal cognition was evaluated on Treatment compliance and adherence (Hill-Bone High Blood Pressure Compliance Scale total score) (β -0.19, 95% CI -0.29 to -0.09, p=<0.001). Cognitive impairment was significantly associated with poorer treatment adherence in elderly hypertensive patients, with each additional point on the MMSE lowering the HBCS nonadherence score by 0.19 points.

synapsesocial.com/papers/6a79bb88f48aafa9d7f36e44https://doi.org/10.2147/cia.s162701
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impaired cognitive function and compliance with antihypertensive drugs in elderly: The Rotterdam Study2001 · 118 citations
  2. 2Adherence problems in elderly patients with hypertension2023 · 4 citations
  3. 3Cognitive Impairment amongst Older Adults with Chronic Medical Conditions and Its Association with Medication Adherence in a Nigerian Tertiary Hospital2024
  4. 4The Impact of Medication Compliance on mild Cognitive Impairment in Hypertensive Individuals: A Cohort Study2024 · 2 citations
  5. 5The Influence of Cognition, Anxiety and Psychiatric Disorders over Treatment Adherence in Uncontrolled Hypertensive Patients2011 · 25 citations