Why the study?
Does influenza vaccination alter prothrombin time in male outpatients receiving chronic warfarin therapy?
Population
21 male outpatients receiving chronic warfarin therapy
Comparison
Influenza vaccination vs Prothrombin times measured before vaccination
Design
Cohort
Follow-up
1 month
Authors
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No significant prothrombin time changes after influenza vaccination in warfarin patients; leaves open need for randomized trials to confirm safety.
Does influenza vaccination alter prothrombin time in male outpatients receiving chronic warfarin therapy?
Influenza vaccination does not significantly alter prothrombin times and appears safe in patients on chronic warfarin therapy.
Benjamin A. Lipsky (1984) studied this question.
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