Why the study?
Does hormone replacement therapy improve arterial stiffness and 24-h ambulatory blood pressure profiles in diabetic postmenopausal women?
Population
12 diabetic postmenopausal women (6 of whom were also hypertensive)
Comparison
Hormone replacement therapy vs Observation period off hormone replacement therapy
Design
RCT, Randomized to two groups (crossover design)
Follow-up
12 months (6 months per phase)
Authors
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HRT confers no BP or vascular benefit in diabetic postmenopausal women; challenges prior hypotheses and supports avoiding it for this purpose.
Does hormone replacement therapy improve arterial stiffness and 24-h ambulatory blood pressure profiles in diabetic postmenopausal women?
Hormone replacement therapy does not appear to improve arterial stiffness or ambulatory blood pressure profiles in diabetic postmenopausal women.
Chris Hayward (2001) studied this question.
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