Population
Mouse flexor digitorum brevis muscles developing in situ from day 1 to 30 after birth
Comparison
Denervation and tissue culture vs Normal development in situ
Design
Preclinical
Follow-up
up to 30 days after birth
Authors
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Innervation plays minimal role in transient Ca2+ current loss during mouse muscle development; leaves open other environmental regulators for further study.
Innervation has little influence on the developmental disappearance of transient Ca2+ channel currents in mouse skeletal muscle, suggesting other environmental factors are required.
Gonoi et al. (1988) studied this question.
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