Key result
Increasing age in healthy males is significantly associated with prolonged phase I duration of pulmonary Vo2 on-kinetics (r=0.74, P<0.0001), rising from 21s at age 20-30 to 32s at age 60-70.
Why the study?
Does age affect the duration of phase I of pulmonary Vo2 on-kinetics during moderate-intensity exercise in healthy humans?
Population
30 healthy male humans divided into three age groups (20-30, 40-50, and 60-70 years, n=10 per group)
Design
Cross-sectional
Authors
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May overestimate phase II tau in older males with fixed fitting; leaves open need for age-specific on-kinetics modeling.
Cross-Sectional (n=30)
Does age affect the duration of phase I of pulmonary Vo2 on-kinetics during moderate-intensity exercise in healthy humans?
Effect estimate: r = 0.74
p-value: p=<0.0001
Phase I duration of pulmonary Vo2 on-kinetics increases with age in healthy humans, which can lead to overestimation of phase II tau if a fixed-duration fitting strategy is used.
Mezzani et al. (2010) conducted a cross-sectional in Healthy (n=30). Increasing age vs. Younger age (20-30 years) was evaluated on Phase I duration of pulmonary Vo2 on-kinetics (r = 0.74, p=<0.0001). Increasing age in healthy males is significantly associated with prolonged phase I duration of pulmonary Vo2 on-kinetics (r=0.74, P<0.0001), rising from 21s at age 20-30 to 32s at age 60-70.
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