Key result
High C-reactive protein levels (>2.5 mg/dL) at hospital admission were independently associated with a significantly increased risk of in-hospital mortality (OR 25) in patients with acute heart failure.
Why the study?
The prognostic role of C-reactive protein during hospitalization in patients with acute HF remains unclear.
Does high C-reactive protein at hospital admission predict in-hospital mortality in patients with acute heart failure admitted to a general hospital ward?
Observational (n=44)
No
Does high C-reactive protein at hospital admission predict in-hospital mortality in patients with acute heart failure admitted to a general hospital ward?
Elevated C-reactive protein at admission is a strong, independent predictor of in-hospital mortality in patients with acute heart failure admitted to a general medical ward.
Answers are grounded in this paper and cite their sources.
High CRP at admission may flag higher in-hospital mortality risk in acute HF; hypothesis-generating and requires prospective validation before guiding care.
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Ferigato et al. (2025) conducted an observational in Acute heart failure (n=44). High C-reactive protein (>2.5 mg/dL) vs. Low C-reactive protein (≤2.5 mg/dL) was evaluated on In-hospital mortality (OR 25, 95% CI 2-335, p=0.046). High C-reactive protein levels (>2.5 mg/dL) at hospital admission were independently associated with a significantly increased risk of in-hospital mortality (OR 25) in patients with acute heart failure.
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