Why the study?
Does the duration of diabetes mellitus differentially affect the risk of coronary heart disease mortality in men and women compared to prior myocardial infarction?
Population
10,871 adults from the 1971-1992 National Health and Nutrition Examination Survey Epidemiologic Follow-up…
Comparison
Recent diabetes mellitus or long-standing… vs Patients with prior myocardial infarction only…
Design
Cohort
Follow-up
1971-1992
Authors
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Challenges assumption of equivalent diabetes-MI CHD risk across sexes; extends cohort data but remains hypothesis-generating.
Does the duration of diabetes mellitus differentially affect the risk of coronary heart disease mortality in men and women compared to prior myocardial infarction?
Long-standing diabetes (≥10 years) in women confers a significantly higher risk of coronary heart disease mortality than a prior myocardial infarction, suggesting a need for more aggressive risk reduction in this subgroup.
Natarajan et al. (2005) studied this question.
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