Population
Cortical collecting duct (CCD) of rat kidney
Comparison
High concentrations of NO donors vs Control conditions
Design
Preclinical
Authors
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NO-superoxide inhibition of rat CCD K+ channels extends tubular signaling data; leaves open human relevance or therapeutic implications.
High concentrations of nitric oxide inhibit basolateral K+ channels in the rat cortical collecting duct through an interaction with superoxide.
Lu et al. (1998) studied this question.
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