Key result
Endovascular treatment led to healing of feet trophic lesions and improved quality of life in an 80-year-old patient with aortic angiosarcoma, though she died 5 months postoperatively.
Why the study?
Aortic angiosarcomas are rare and difficult to diagnose due to nonspecific clinical and radiological symptoms, often resulting in late diagnosis and poor prognosis.
Case Report (n=1)
No
Endovascular treatment with CERAB and embolectomy is a feasible, less invasive palliative option for critical limb ischemia caused by aortic angiosarcoma, providing symptom relief and limb salvage despite poor overall survival.
May offer palliative limb salvage in aortic angiosarcoma with critical limb ischemia; leaves open need for prospective data on durability and survival.
Aortic angiosarcomas (AAS) occur in approximately one case per million people annually and are often difficult to diagnose due to their nonspecific clinical and radiological symptoms. An 80-year-old female presented with the absence of pulses of both lower limbs and feet tissue loss. A contrast-enhanced computed tomography (CT) scan showed the occlusion of the infrarenal abdominal aorta extending to the aortic bifurcation, involving both common and external iliac arteries up to the superficial femoral artery bilaterally. A Fogarty embolectomy of both side femoral axes was performed followed by a covered endovascular reconstruction of the aortic bifurcation (CERAB) with a covered stent graft and two covered iliac stents placed in a kissing stent configuration. Histological examination of the Fogarty embolectomy samples revealed an aortic localization of epithelioid angiosarcoma. Healing of feet trophic lesions was observed 2 months after surgery, regardless of physical and rehabilitation team intervention progressive cachexia and physical deterioration led the patient to death 5 months postoperatively. Due to their nonspecific clinical presentation, AAS are typically late diagnosed with poor prognosis despite treatment. Endovascular treatment was chosen as the only feasible option, given the high risk of limb loss and poor general health conditions. Moreover, it led to significant improvement in patient’s quality of life with no postoperative complications. Endovascular treatment associated with a physical and rehabilitation program may be advised as a less invasive alternative, for palliative or emergent clinical presentation in order to avoid short-term complications with poor impact on survival and quality of life.
No takes yet. Share an insight, caveat, or question.
Galassi et al. (2025) conducted a case report in Infrarenal Aortic Epithelioid Angiosarcoma causing Critical Limb Ischemia (n=1). Endovascular treatment (Fogarty embolectomy and CERAB) was evaluated on Clinical improvement and survival. Endovascular treatment led to healing of feet trophic lesions and improved quality of life in an 80-year-old patient with aortic angiosarcoma, though she died 5 months postoperatively.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: