Key result
Fatal primary aortic angiosarcoma emerges years after EVAR, highlighting need for early tissue diagnosis.
Why the study?
Angiosarcoma arising in the aortic wall after endovascular aneurysm repair is an exceptionally rare but devastating complication.
Case Report (n=1)
Atypical symptoms after EVAR should raise suspicion for rare but aggressive complications like aortic angiosarcoma, necessitating early tissue diagnosis.
Consider angiosarcoma in atypical post-EVAR cases; extends differential for graft infection mimics but remains hypothesis-generating.
Angiosarcoma arising in the aortic wall after endovascular aneurysm repair (EVAR) is an exceptionally rare but devastating complication. We report a case of a 76-year-old man who developed progressive systemic symptoms and persistent imaging abnormalities years after EVAR. Despite extensive workup and empirical treatment for graft infection and aortitis, diagnosis was delayed until biopsy revealed angiosarcoma. The clinical course was rapidly progressive and ultimately led to death. Atypical symptoms after EVAR should raise suspicions of malignancy. Early tissue diagnosis is essential for the timely recognition of this aggressive and frequently misdiagnosed entity, which often carries a poor prognosis.
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Koussayer et al. (2025) conducted a case report in Primary aortic angiosarcoma following endovascular aneurysm repair (n=1). Endovascular aneurysm repair (EVAR) was evaluated on Clinical course and diagnosis. A 76-year-old man developed a rapidly progressive and fatal primary aortic angiosarcoma years after endovascular aneurysm repair, highlighting the need for early tissue diagnosis of atypical symptoms.
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