Key result
Percutaneous annuloplasty and transcatheter edge-to-edge repair both achieved high technical and device success rates (98% and 97%, respectively) and reduced tricuspid regurgitation severity by approximately two grades.
Why the study?
T-TEER and percutaneous annuloplasty are the most widely used techniques for TR in Europe, but comparative data on procedural characteristics and learning curves in a real-world cohort were needed.
Does percutaneous annuloplasty compared to T-TEER improve procedural characteristics and TR reduction in patients with severe to torrential tricuspid regurgitation?
Cohort (n=122)
Yes
Does percutaneous annuloplasty compared to T-TEER improve procedural characteristics and TR reduction in patients with severe to torrential tricuspid regurgitation?
Absolute Event Rate: 98% vs 97%
p-value: p=0.502
Both percutaneous annuloplasty and T-TEER are highly effective at reducing severe tricuspid regurgitation with excellent technical success, though T-TEER is associated with shorter procedure times and fewer periprocedural complications.
T-TEER shows shorter procedure times than annuloplasty in severe TR; leaves open optimal device selection pending randomized trials.
Background: In recent years, new interventional therapies for tricuspid regurgitation (TR) demonstrated their effectiveness in reducing TR severity and improving symptoms. Currently, tricuspid transcatheter edge-to-edge repair (T-TEER) and percutaneous annuloplasty are the most widely used techniques in Europe. In this retrospective study, we compared procedural characteristics and learning curves of both TR devices in a real-world cohort. Material and methods: Eligible patients with severe to torrential TR underwent either percutaneous annuloplasty or T-TEER as recommended by the local heart team. Patients with combined mitral and tricuspid interventions were excluded from the analysis. The study focused on procedural characteristics, TR reduction and learning curves. Results: = 58) with a technical and device success rate of 98% and 97%, respectively. Reasons for technical failure included right coronary artery (RCA) dissection prior to percutaneous annuloplasty, and two single leaflet device attachments (SLDA) during T-TEER implantation. The mean improvement of TR severity was 2.4 ± 0.8 degrees after T-TEER and 2.5 ± 0.8 after percutaneous annuloplasty. T-TEER procedures were shorter in terms of both procedure time and radiation exposure, while percutaneous annuloplasty, although taking longer, showed a significant reduction in procedure time over the course of the analysed period. Conclusion: In summary, both interventional therapies reduce TR severity by approximately two degrees when used in the appropriate anatomy. The learning curve for annuloplasty group showed a significant decrease of procedure times.
No takes yet. Share an insight, caveat, or question.
Mattig et al. (2023) conducted a cohort in Severe to torrential tricuspid regurgitation (n=122). Percutaneous annuloplasty vs. Transcatheter edge-to-edge repair (T-TEER) was evaluated on Technical and device success (p=0.502). Percutaneous annuloplasty and transcatheter edge-to-edge repair both achieved high technical and device success rates (98% and 97%, respectively) and reduced tricuspid regurgitation severity by approximately two grades.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: