Population
Myofibrils
Comparison
Proteolysis with trypsin in the presence of 10… vs Proteolysis with trypsin in the presence of 1 mM…
Design
Preclinical
Authors
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Animal proteolysis data warrant no clinical change; leaves open whether EDTA yields superior human cardiac myosin subfragments.
Demonstrates that proteolysis of myofibrils in the presence of EDTA yields a single enzymatically active myosin subfragment similar to heavy-meromyosin subfragment 1.
Biró et al. (1973) studied this question.
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