Population
Herpes simplex virus (HSV-1 Angelotti) during serial passages at high multiplicity of infection
Design
Preclinical
Authors
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Identifies origins of two defective HSV-1 DNA classes; leaves open roles in viral dynamics and requires in vivo validation.
The study identifies the genomic origins of two classes of defective HSV-1 Angelotti DNA generated during high MOI passages.
Kaerner et al. (1979) studied this question.
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