Key result
A 12-week continuous aerobic exercise training program significantly improved 6-minute walk test distance (from 208.65 to 360.98), ejection fraction, and heart rate variability in post-MI men.
Why the study?
Post-MI autonomic imbalance and decreased heart rate variability increase adverse risk and mortality, while LV remodeling carries significant prognostic consequences.
Does a supervised continuous aerobic exercise program improve heart rate variability, functional capacity, and left ventricular remodeling in middle-aged male patients 1 month post-myocardial infarction?
Does a supervised continuous aerobic exercise program improve heart rate variability, functional capacity, and left ventricular remodeling in middle-aged male patients 1 month post-myocardial infarction?
A 12-week supervised continuous aerobic exercise program significantly improves functional capacity, heart rate variability, and left ventricular ejection fraction in middle-aged men recovering from a recent myocardial infarction.
May support supervised aerobic exercise post-MI; hypothesis-generating pending RCTs.
BackgroundAfter myocardial infarction (MI), elevated sympathetic activity and/or reduced parasympathetic activity are observed. As a result, these patients have a decreased heart rate variability (HRV), which has been linked to an elevated risk of adverse effects and death. Following MI, the remodeling of the left ventricle (LV) is a complex and multifactorial mechanism, with therapeutic and prognostic consequences. Medications that reduced LV improved survival and standard of living.AimWe aimed to evaluate the effect of continuous exercise remodeling training on HRV, function capacity [6-min walk test (6MWT)], and LV remodeling in patients who had experienced MI.Patients and methodsOne month after having MI, 40 eligible male patients aged 45–55 years old were recruited. Patients underwent a supervised intensive CR recovery program consisting of continuous aerobic exercise. Evaluation of the effect of this program was done by clinical examination, transthoracic echocardiography to calculate ejection fraction, 6MWT, and Holter ECG 24 h to measure different HRV parameters. All patients received 36 training sessions (three times/week for 12 weeks). The results of these procedures were compared before and after this program.ResultsAccording to the current results, the mean pretreatment and posttreatment 6MWT values were 208.65 ± 24.62 and 360.98 ± 109.78, respectively, with an improvement percentage of 55.79%. Irrespective of time or frequency domain, HRV parameters were markedly improved after treatment compared with pretreatment values. Ejection fraction % was significantly improved by 14.82%.ConclusionExercise training tends to be a beneficial clinical technique for patients with MI who have an unbalanced autonomic function, which is manifested by improvement of HRV parameters. Exercise training improves blood pressure and resting heart rate. Improvement of 6MWT parameters occurred after exercise training.
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Bordy et al. (2021) studied Myocardial infarction (n=40). Continuous aerobic exercise training vs. Pretreatment (baseline) was evaluated on 6-minute walk test (6MWT). A 12-week continuous aerobic exercise training program significantly improved 6-minute walk test distance (from 208.65 to 360.98), ejection fraction, and heart rate variability in post-MI men.
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