Key result
Remimazolam significantly reduced the incidence of emergence agitation compared to propofol in elderly patients undergoing hip replacement (10% vs 33%, P < 0.05).
Why the study?
The comparative effects of remimazolam versus propofol on emergence agitation in elderly patients undergoing hip replacement remained to be determined.
Does remimazolam reduce emergence agitation compared to propofol in elderly patients undergoing hip replacement?
RCT (n=60)
No
Does remimazolam reduce emergence agitation compared to propofol in elderly patients undergoing hip replacement?
Absolute Event Rate: 10% vs 33%
p-value: p=< 0.05
Remimazolam reduces the incidence of emergence agitation and postoperative adverse events compared to propofol in elderly patients undergoing hip replacement.
No takes yet. Share an insight, caveat, or question.
Remimazolam was associated with lower emergence agitation than propofol; hypothesis-generating and should not yet change practice in elderly hip replacement.
Duan et al. (2023) conducted an RCT in Hip replacement (n=60). Remimazolam vs. Propofol was evaluated on Incidence of emergence agitation (EA) (p=< 0.05). Remimazolam significantly reduced the incidence of emergence agitation compared to propofol in elderly patients undergoing hip replacement (10% vs 33%, P < 0.05).
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