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This review outlines the metabolic abnormalities promoting atherosclerosis and current pharmacological and revascularization strategies for treating and preventing coronary artery disease in diabetics.
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This review highlights the accelerated coronary atherosclerosis in diabetics and summarizes the pharmacological and revascularization strategies to manage cardiovascular disease in this high-risk population.
Diabetes has become a public health crisis. With the incidence of obesity rising in the United States, the number of diabetics will grow considerably. Of greatest concern is the impact this trend will have on cardiovascular disease. Diabetics demonstrate accelerated coronary atherosclerosis, and the prognosis is worse following cardiac events. Moreover, our interventions have achieved uneven success in treating this subset of patients. This paper will review the metabolic abnormalities that promote atherosclerosis in diabetics and the current methods for treating and preventing the development of coronary artery disease in diabetics, principally through a combination of medications and revascularization.
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Mangalmurti et al. (2004) conducted a review in Cardiovascular disease in diabetics. Pharmacology and revascularization was evaluated. This review outlines the metabolic abnormalities promoting atherosclerosis and current pharmacological and revascularization strategies for treating and preventing coronary artery disease in diabetics.
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