Key result
Prehospital DOAC use in geriatric hip fracture patients undergoing early surgery was associated with higher 30-day readmission (21% vs 5.3%, P=0.05) and longer surgical delay (28.9h vs 21.4h, P=0.03).
Why the study?
Does prehospital DOAC use worsen surgical outcomes in geriatric patients undergoing early surgical fixation for proximal femur fractures?
Population
93 geriatric patients with proximal femur fractures undergoing early surgical fixation.
Comparison
Prehospital use of direct oral anticoagulants. vs Control patients not receiving direct oral…
Design
Case-control
Follow-up
1 year
Authors
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Signals potential readmission risk with prehospital DOACs; leaves open optimal reversal and timing protocols in geriatric hip fracture surgery.
Case-Control (n=93)
Yes
Does prehospital DOAC use worsen surgical outcomes in geriatric patients undergoing early surgical fixation for proximal femur fractures?
Absolute Event Rate: 21% vs 5.3%
p-value: p=0.05
Early surgical intervention for hip fractures in geriatric patients on DOACs does not lead to worse bleeding or survival outcomes, suggesting routine surgical delays may be unwarranted.
Franklin et al. (2018) conducted a case-control in Geriatric proximal femur fractures (n=93). Prehospital direct oral anticoagulants (DOAC) vs. No DOAC (control) was evaluated on Readmission within 30 days (p=0.05). Prehospital DOAC use in geriatric hip fracture patients undergoing early surgery was associated with higher 30-day readmission (21% vs 5.3%, P=0.05) and longer surgical delay (28.9h vs 21.4h, P=0.03).
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