Why the study?
Is enteroviral infection associated with the pathogenesis of Keshan disease?
Population
14 cases with histologically confirmed subacute or chronic Keshan disease and 11 negative controls from…
Design
Case-control
Authors
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Supports enteroviral role in Keshan disease; hypothesis-generating and leaves open causal confirmation.
Is enteroviral infection associated with the pathogenesis of Keshan disease?
Enteroviral genomic sequences, particularly coxsackievirus B, are highly prevalent in the myocardium of patients with Keshan disease, supporting an aetiological role for enteroviral infection in this endemic cardiomyopathy.
Yanan Li (2000) studied this question.
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