Effectiveness and Safety of Fecal Microbiota Transplantation for Clostridioides Difficile Infection: Results From a 5344-Patient Cohort Study

Fecal microbiota transplantation (FMT) is recommended for the prevention of recurrent Clostridioides difficile infection (CDI).1 Randomized trials have reported promising efficacy and safety among patients treated with FMT following standard of care (SOC) CDI antibiotics compared with SOC CDI antibiotics alone. However, these trials are small, with methodological limitations.2 Potential adverse events, especially in immunocompromised patients, highlight the importance of ensuring continued data collection on clinical outcomes.