Key result
Ketamine anesthesia in children with pulmonary arterial hypertension was not associated with increased complications (overall cardiac arrest incidence 1.6%, 0% procedure-related mortality).
Why the study?
Does ketamine administration during general anesthesia increase peri-procedural complications in children with pulmonary arterial hypertension?
Population
68 children with pulmonary arterial hypertension undergoing 192 procedures with general anesthesia. Median…
Comparison
Ketamine administration during general anesthesia vs General anesthesia without ketamine
Design
Cohort
Follow-up
48 hours post-procedure
Authors
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Supports ketamine anesthesia without increased complications in pediatric pulmonary arterial hypertension; leaves open need for randomized confirmation.
Cohort (n=68)
Does ketamine administration during general anesthesia increase peri-procedural complications in children with pulmonary arterial hypertension?
Ketamine appears to be a safe anesthetic option for children with pulmonary arterial hypertension undergoing procedures, with no associated increase in perioperative complications.
Williams et al. (2009) conducted a cohort in Pulmonary arterial hypertension (n=68). Ketamine anesthesia vs. Anesthesia without ketamine was evaluated on Peri-procedural complications (during or within 48 h of the procedure). Ketamine anesthesia in children with pulmonary arterial hypertension was not associated with increased complications (overall cardiac arrest incidence 1.6%, 0% procedure-related mortality).
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