Why the study?
Does etomidate anesthesia improve seizure duration compared to methohexital in patients undergoing electroconvulsive therapy?
Does etomidate anesthesia improve seizure duration compared to methohexital in patients undergoing electroconvulsive therapy?
Etomidate anesthesia is safe for ECT but offers no benefit over methohexital in lengthening seizure duration.
Etomidate remains acceptable for ECT; leaves open optimal anesthetic selection pending randomized trials.
AbstractEighteen patients undergoing a course of electroconvulsive therapy (ECT) alternately received methohexital and etomidate anesthesia. No difference could be found in seizure duration between the two anesthetics. Adrenocorticotropic hormone (ACTH) stimulation tests in eight patients revealed no abnormality after repeated injections of etomidate. We find that etomidate anesthesia, although safe for ECT, offers no benefit over methohexital in lengthening seizure duration.
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Boccio et al. (1989) studied this question.
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