Why the study?
Does the choice and dose of hypnotic (methohexital, propofol, or etomidate) affect seizure duration and cognitive recovery in patients undergoing ECT?
Population
n=10 outpatients with major depressive disorders receiving maintenance ECT
Comparison
IV bolus injection of methohexital or propofol… vs Cross-over comparison between the different…
Design
RCT, randomized, cross-over study
Follow-up
Immediate post-ECT recovery period
Authors
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Etomidate may be prioritized for ECT to ensure adequate seizures; extends RCT evidence guiding anesthetic choice in procedural psychiatry.
Does the choice and dose of hypnotic (methohexital, propofol, or etomidate) affect seizure duration and cognitive recovery in patients undergoing ECT?
Etomidate preserves ECT-induced seizure duration better than propofol or methohexital, making it a useful alternative despite slightly prolonged cognitive recovery.
Avramov et al. (1995) studied this question.