Key result
Impaired glucose tolerance in women was associated with worse metabolic variables (P<0.01), which were largely eliminated after matching for visceral adipose tissue, except for higher triglycerides.
Why the study?
Does impaired glucose tolerance independently contribute to the deterioration of the metabolic profile in women after accounting for visceral adipose tissue?
Cross-Sectional (n=249)
Does impaired glucose tolerance independently contribute to the deterioration of the metabolic profile in women after accounting for visceral adipose tissue?
p-value: p=<0.01
Visceral adipose tissue accumulation is a major driver of metabolic deterioration in women with IGT, though hypertriglyceridemia appears independently associated with IGT.
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VAT largely explains metabolic differences in women with IGT; leaves independent triglyceride link hypothesis-generating for prospective study.
Pascot et al. (2001) conducted a cross-sectional in Impaired glucose tolerance (n=249). Impaired glucose tolerance vs. Normal glucose tolerance was evaluated on Metabolic variables including lipids, insulin, and blood pressure (p=<0.01). Impaired glucose tolerance in women was associated with worse metabolic variables (P<0.01), which were largely eliminated after matching for visceral adipose tissue, except for higher triglycerides.
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