Why the study?
Do clinical features reliably distinguish rotavirus from non-rotavirus gastroenteritis in hospitalized children?
Do clinical features reliably distinguish rotavirus from non-rotavirus gastroenteritis in hospitalized children?
Clinical signs, including upper respiratory symptoms, do not reliably differentiate rotavirus from non-rotavirus gastroenteritis in hospitalized children.
Clinical signs do not distinguish rotavirus gastroenteritis; observational data challenge a distinct syndrome and leave testing implications open.
In a prospective study of children referred to hospital, rotavirus was identified in 37% of 128 patients with acute gastroenteritis. As compared with patients with non-rotavirus gastroenteritis, those with rotavirus gastroenteritis showed the following clinical characteristics: Age between 5 months and 4 years. Occurrence of the rotavirus infection almost exclusively during the winter season. Severe vomiting. Absence of gross blood in the stools. However, these signs did not form a safe basis for the clinical diagnosis of rotavirus gastroenteritis. One or more signs of upper respiratory illness were observed in 36% of the patients with rotavirus gastroenteritis and in 35% of those with non-rotavirus gastroenteritis. Consequently, the existence of a rotavirus syndrome is questioned. It is argued that upper respiratory illnesses in patients with rotavirus gastroenteritis could be due to a separate infection occurring coincidentally.
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Hjelt et al. (1985) studied this question.
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