Why the study?
Is the severity of rotavirus gastroenteritis symptoms related to the infecting viral strain in children?
Population
401 Italian children with acute rotavirus gastroenteritis
Comparison
Infection with specific rotavirus strains vs Infection with other rotavirus strains
Design
Cohort
Authors
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G2P[4] strains were associated with greater severity in children; hypothesis-generating for strain surveillance but should not yet change practice.
Is the severity of rotavirus gastroenteritis symptoms related to the infecting viral strain in children?
The severity of rotavirus gastroenteritis in children is associated with specific viral strain characteristics, with G2P[4] strains causing more severe disease.
Cascio et al. (2001) studied this question.
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