Why the study?
Does ascorbic acid pretreatment prevent contractile impairment and Ca2+ transient decrease caused by electrical shock in isolated rat cardiomyocytes?
Does ascorbic acid pretreatment prevent contractile impairment and Ca2+ transient decrease caused by electrical shock in isolated rat cardiomyocytes?
Ascorbic acid pretreatment prevents contractile impairment and decreased calcium transients in cardiomyocytes following electrical shock by eliminating free radicals.
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Hypothesis-generating in isolated rat cardiomyocytes; does not support clinical ascorbic acid pretreatment before defibrillation.
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Tsai et al. (2008) studied this question.
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