Population
25 mongrel puppies
Design
Preclinical
Follow-up
varying intervals after the second infarct
Authors
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Supports repeated infarction hypothesis for Perthes in puppy model; leaves open human confirmation before any practice change.
Experimental simulation in puppies suggests that Perthes disease in humans may be caused by multiple episodes of infarction.
Sanchís et al. (1973) studied this question.
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